GM-CSF Protéine

N° du produit ABIN5775831

Protéine Recombinant GM-CSF exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour GM-CSF Protéine (ABIN5775831)

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 98 % pure

Détail du produit

Séquence: MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

Attributs du produit: Purified recombinant Human GM-CSF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7 units/mg.

niveau d'endotoxine: < 0.1 ng per μg (1 EU/μg).

Information d'application

Indications d'application: Each Investigator should determine their own optimal working dilution for specific applications.

Commentaires:

Biological activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is approx. 0.05 ng/mL, corresponding to a specific activity of approx. 2 x 10^7 units/mg.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with distilled water to a concentration of 0.1-1.0 mg/mL.

Buffer: Lyophilized from 10 mM HoAc.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Détail du antigène

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: GM-CSF

Sujet: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.
Alternative Names: CSF-2 protein, MGI-1GM protein, Granulocyte/Macrophage Colony-Stimulating Factor protein, pluripoietin-alpha protein, GM-CSF protein

Poids moléculaire: 14.2 kDa

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin